Oral pharmaceutical products containing...

A - Human Necessities – 61 – K

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Details

A61K 31/565 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/57 (2006.01) A61P 15/12 (2006.01) A61P 15/18 (2006.01)

Patent

CA 2470703

A pharmaceutical dosage unit for oral administration to a human female comprising a therapeutically effective amount of 17.beta.-estradiol-3-lower Alkanoate, most preferably 17.beta.-estradiol-3-acetate, and pharmaceutically acceptable carrier is disclosed. Also disclosed is a method for treating a human female in need of 17.beta.-estradiol and a contraceptive method by oral administration of the pharmaceutical dosage unit and a method of preparing a pharmaceutical composition that may be used to form the pharmaceutical dosage unit of the invention.

L'invention concerne une unité posologique pharmaceutique destinée à être administrée par voie orale à une femme et renfermant une quantité efficace sur le plan thérapeutique de 17.beta.-estradiol-3 alcanoate inférieur, idéalement 17.beta.-estradiol-3-acétate, et un excipient acceptable sur le plan pharmaceutique. L'invention concerne également une méthode de traitement d'une femme nécessitant 17.beta.-estradiol et une méthode contraceptive consistant en une administration orale de l'unité posologique pharmaceutique, ainsi qu'un procédé de préparation d'une composition pharmaceutique pouvant être utilisée aux fins de constitution de l'unité posologique pharmaceutique selon l'invention.

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