Oral preparation useful in measuring capacity to metabolize...

A - Human Necessities – 61 – K

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A61K 49/00 (2006.01)

Patent

CA 2616788

It is intended to provide an oral preparation which is usable in diagnosing the presence or absence of an abnormality in the capacity to metabolize pyridine, a pyrimidine metabolic speed and so on at a high accuracy with little difference from individual to individual. An isotope-labeled compound and/or a pyrimidine metabolite compound (a) are mixed with a sugar and/or a sugar alcohol (b) and milled. By using the powdery material thus obtained, an oral preparation is produced.

L~invention a pour objet une préparation orale utilisable pour le diagnostic de la présence ou de l~absence d'une anomalie de la capacité de métaboliser la pyridine, d~une vitesse de métabolisation de la pyrimidine et autres, avec grande exactitude et peu de différences d'un individu à un autre. Un composé marqué aux isotopes et/ou un composé métabolite de la pyrimidine sont (a) mélangés à un sucre et/ou un alcool de sucre (b) et broyés. Une préparation orale est obtenue en utilisant le matériau poudreux ainsi obtenu.

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