A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/319.1
A61K 6/00 (2006.01) A61K 31/12 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/77 (2006.01)
Patent
CA 1227139
ABSTRACT OF THE DISCLOSURE An oral composition for treating gingivitis and periodontitis comprising an oral vechicle and an effective amount of the water insoluble antigingivitis agent, imidazoyl-1-(p-chlorophenoxy)3-3-dimethyl 2-butanone solubilized in a nonionic compound containing a mixture of hydrophobic and hydrophilic groups of sufficient length to effect solubilization in an aqueous vehicle, in the weight ratio of 1:1 to 25:1 and preferably 3:1 to 25:1 solubilizer:imidazolyl compound, said agent being selectively effective against the gram negative anaerobic micro-organisms associated with periodontitis.
441362
Davis Calvin B.
Gaffar Abdul
Vasers Margita L.
Colgate-Palmolive Company
Smart & Biggar
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