Oral product for controlling gingivitis

A - Human Necessities – 61 – K

Patent

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167/319.1

A61K 6/00 (2006.01) A61K 31/12 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/77 (2006.01)

Patent

CA 1227139

ABSTRACT OF THE DISCLOSURE An oral composition for treating gingivitis and periodontitis comprising an oral vechicle and an effective amount of the water insoluble antigingivitis agent, imidazoyl-1-(p-chlorophenoxy)3-3-dimethyl 2-butanone solubilized in a nonionic compound containing a mixture of hydrophobic and hydrophilic groups of sufficient length to effect solubilization in an aqueous vehicle, in the weight ratio of 1:1 to 25:1 and preferably 3:1 to 25:1 solubilizer:imidazolyl compound, said agent being selectively effective against the gram negative anaerobic micro-organisms associated with periodontitis.

441362

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