A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4164 (2006.01) A61K 9/28 (2006.01) A61P 13/02 (2006.01)
Patent
CA 2390933
The invention is to provide an oral solid pharmaceutical that is uniform in the content of KRP-197, having bladder--selective anticholinergic activity, being a therapeutic drug for pollakiuria and urinary incontinence, and being active with a very low dosage, that can be taken quantitatively, and that is easy in the handling. Since KRP-197 becomes unstable to light under the influence of additives, the invention is to select the additives to be used and to obtain a pharmaceutical with high stability. By formulating KRP-197 with drug-making carriers, a pharmaceutical that is uniform in the content, capable of taking quantitatively and easy in the handling has been provided. Furthermore, by using polyvinyl pyrrolidone for binder and by making into tablet coated with a coating base containing titanium dioxide and ferric oxide, a pharmaceutical capable of taking quantitatively and excellent in the light stability has been provided.
L'invention concerne une préparation solide orale renfermant un contenu homogène de KPR-197, qui constitue un médicament contre les mictions fréquentes et l'incontinence urinaire, qui possède une activité anticholinergique sélective pour la vessie, et qui est efficace même en quantité extrêmement petite. La préparation permet d'administrer quantitativement ledit médicament, et peut être facilement manipulée. Du fait que KPR-197 devient instable à la lumière sous l'influence d'un additif, il est important d'utiliser des additifs sélectionnés de façon à produire une préparation très stable, Ladite préparation comprend KPR-197 et un support. En utilisant du polyvinylpyrrolidone comme liant de façon à former des comprimés enrobés d'une base d'enrobage constituée d'oxyde de titane et de sesquioxyde de fer, il est également possible d'administrer quantitativement la préparation, et d'obtenir une excellente stabilité à la lumière.
Ohishi Masahiko
Ohyama Toshinori
Yamamoto Yasuhiro
Borden Ladner Gervais Llp
Kyorin Pharmaceutical Co. Ltd.
LandOfFree
Oral solid preparation comprising... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oral solid preparation comprising..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oral solid preparation comprising... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1928090