Oral testosterone delivery system with improved sustained...

Details Oral testosterone delivery system with improved sustained... Oral testosterone delivery system with improved sustained...

A - Human Necessities

61

K

A61K 31/568 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01)

Patent

CA 2505951

An oral testosterone delivery system with sustained release properties where the micronized testosterone is present as a tablet, bolus, capsule, powder, liquid or suspension and, optionally, at least part of the testosterone is microencapsulated; in a preferred embodiment, the testosterone is present in a solid lipid suspension, wherein the suspension exhibits pseudotropic and/or thixotropic flow properties when melted.

L'invention concerne un système d'administration de testostérone par voie orale possédant des propriétés de libération prolongée, la testostérone micronisée se présentant sous forme de comprimé, de dragée, de gélule, de poudre, de liquide ou de suspension, au moins une partie de la testostérone étant éventuellement microencapsulée. Dans un mode de réalisation préféré, la testostérone se présente sous forme de suspension lipidique solide, la suspension présentant des propriétés d'écoulement pseudotropique et/ou thixotropique lorsqu'elle est fondue.

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