Oral therapeutic or preventive drugs for pollakiuria and...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/04 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61P 13/00 (2006.01) A61P 13/02 (2006.01) A61P 13/10 (2006.01) A61P 25/20 (2006.01) C07D 239/42 (2006.01) C07D 277/42 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2485869

Oral therapeutic or preventive drugs for pollakiuria and urinary incontinence or oral sleep inducers, which contain as the active ingredient compounds represented by the general formula (I) or pharmacologically acceptable salts thereof and exhibit excellent peroral absorbability: (I) wherein R1 is hydrogen or linear or branched alkyl having 1 to 3 carbon atoms; R2 is hydrogen or isopropyl; and Ar is an unsubstituted heteroaromatic group having two heteroatoms.

L'invention concerne des médicaments préventifs ou thérapeutiques, par voie orale, contre la pollakiurie et l'incontinence urinaire, ou inducteurs de sommeil, contenant en tant que principes actifs des composés représentés par la formule générale (I) : ou des sels de ces composés, acceptables sur le plan pharmaceutique, qui possèdent une excellente absorbabilité orale, dans laquelle R1 représente un atome d'hydrogène ou un groupe alkyle linéaire ou ramifié de 1 à 3 atomes de carbone, R2 représente un atome d'hydrogène ou un groupe isopropyle, et Ar représente un groupe hétéroaromatique contenant deux hétéroatomes.

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