A - Human Necessities – 61 – C
Patent
A - Human Necessities
61
C
A61C 8/00 (2006.01) A61L 27/38 (2006.01) C12N 5/071 (2010.01) C12N 11/00 (2006.01)
Patent
CA 2644489
A method for treating an oral condition of a subject by grafting cultured tissue constructs to the oral tissue. The cultured tissue constructs comprise cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues their cells are derived and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention comprise cells derived from human tissue.
L'invention concerne une méthode pour traiter une affection orale d'un sujet en greffant des constructions de tissu de culture sur un tissu oral. Les constructions de tissu de culture comprennent des cellules cultivées et des composants extracellulaires de matrice produits de façon endogène sans nécessiter de composants exogènes de matrice ou de support de réseau ou de membres d'échafaudage. Certaines constructions de tissu selon l'invention comprennent plusieurs couches cellulaires ou plus d'un type de cellule. Les constructions de tissu selon l'invention ont des caractéristiques morphologiques et fonctionnelles semblables aux tissus dont leurs cellules dérivent, et leur résistance les rend facilement manipulables. Des constructions préférées de tissu de culture de l'invention comprennent des cellules dérivées de tissu humain.
Eklund Dario C.
Finlayson & Singlehurst
Organogenesis Inc.
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