Oral vehicle for systemic pharmaceuticals

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/10 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2623306

Systemic drug delivery means comprises boluses of a semi-solid agar gel, each containing active ingredients, packed singly or in co-operating sets in blister packs, or loose in a container. When placed in the mouth the bolus is disrupted, comes apart, and releases the active ingredients. Sialogogues, flavours, and other additives assist in swallowing. Grains of the active ingredients may be encapsulated inside harder gel capsules.Active ingredients include over-the-counter medications and prescription medications. Applications include self-medication particularly in water-free situations such as public transport, medication for children, stroke victims or the aged.

La présente invention concerne des moyens d~administration de médicaments systématiques comprenant des bolus constitués d~un gel d~agar semi-solide, chacun contenant des ingrédients actifs,emballés individuellement ou en jeux coopératifs dans des plaquettes à alvéoles ou en vrac dans une boîte. Lorsqu~il est placé dans la bouche, le bolus se rompt, se défait et libère les ingrédients actifs. Des sialagogues, des parfums et autres additifs aident l~ingestion. Les grains d~ingrédients actifs peuvent être encapsulés dans des capsules de gel plus dur. Ces ingrédients comprennent des médicaments vendus sans prescription ou sous prescription. Les applications de l~invention comprennent la prise autonome de médicaments particulièrement dans des situations sans ingestion d~eau comme par exemple dans les transports en commun, pour les enfants, les victimes d~infarctus ou les personnes âgées.

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