Oral veterinary fluoroquinolone antibacterial composition...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/495 (2006.01) A61K 9/00 (2006.01) A61K 31/47 (2006.01) A61K 31/496 (2006.01)

Patent

CA 2222950

The present invention concerns a formulation for an oral veterinary composition containing a fluoroquinolone antimicrobial agent or a pharmaceutically acceptable salt thereof, and a method of treating a microbial infection in a ruminant. The present veterinary composition, when administered orally to a ruminating animal (e.g., a cow or a feedlot calf), allows the fluoroquinolone to be readily and extensively absorbed from the rumen into the circulating blood and provides an unexpectedly extended duration of therapeutic antimicrobial blood level.

La présente invention concerne une formulation vétérinaire administrée per os contenant comme agent antibactérien une fluoroquinolone, ou un sel de celle-ci pharmaceutiquement acceptable ainsi qu'un procédé pour traiter des infections microbiennes chez un ruminant. La présente composition vétérinaire, quand elle est administrée per os à un ruminant (vache ou veau élevé en batterie), permet une absorption facile et complète de la fluoroquinolone depuis le rumen dans le sang et elle permet de conserver un niveau thérapeutique de l'agent antibactérien dans le sang pendant une durée inattendue.

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