Orally active renin inhibitors

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/08 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07D 205/04 (2006.01) C07D 211/26 (2006.01) C07D 211/58 (2006.01) C07D 211/74 (2006.01) C07D 333/24 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/06 (2006.01) C07D 409/12 (2006.01) C07D 413/04 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07K 5/02 (2006.01) C07K 5/023 (2006.01) C07K 5/065 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2034315

ORALLY ACTIVE RENIN INHIBITORS Abstract This invention relates to compounds of the formula Image I wherein Q, Z, D, E, R3, R4, R5 and R6 are defined as below, and the pharmaceutically acceptable salts thereof are disclosed. The compounds are useful as antihypertensive agents.

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