A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A23K 1/00 (2006.01) A23K 1/16 (2006.01) A61K 9/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2175077
A dosage form for orally administering chemical or medicinal substances such as vitamins, trace elements, amino acids, nutritive substances, vaccines, etc., to domestic or wild animals, and a method for preparing same, are disclosed. Said dosage form includes: a porous water-soluble central core containing binders selected from polypeptides, polysaccharides, polymers and colloids, and/or diluents selected from polyols, metal oxides, carbonates, phosphates and microcrystalline cellulose, and an effective amount of at least one bioactive substance; and a palatable hydrophobic outer layer containing at least one lipid substance selected from fatty alcohols, fatty acids, glycerol esters, hydrogenated oils, waxes, paraffin, lanolin, coconut oil and fatty acid salts; a polymeric agent for modulating the disintegration and adhesion of said outer layer; and natural or synthetic palatable substances.
Forme galénique pour 1'administration orale de substances chimiques ou médicamenteuses, telles que vitamines, oligo-éléments, amino- acides, substances nutritionnelles, vaccins etc.., à des animaux domestiques ou sauvages et son procédé d'obtention. Ladite forme galénique comprend: un noyau central, hydrosoluble, et poreux, qui comprend: des liants sélectionnés parmi des polypeptides, des polysaccharides, des polymères et des colloides, et/ou des diluants sèlectionnés parmi des polyols, des oxydes métalliques, des carbonates, des phosphates ou la cellulose microcristalline, et une quantitié efficace d'au moins une substance bioactive et une couche externe, à caractère hydrophobe et appétant, qui comprend: au moins une substance lipidique choisie parmi les alcools gras, les acides gras, les esters de glycérol, les huiles hydrogénées, les cires, la paraffine, la lanoline, l'huile de coprah et les sels d'acides gras; un agent de modulation du délitement et de l'adhésion de ladite couche exteme, choisi parmi des polymères, et des substances appétentes, naturelles ou synthétiques.
Aubert Andre
Derrieu Guy
Raynier Bernard
Schumacher Carolin L.
Laboratoires Virbac
Marcus & Associates
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