Orally-administered live bacterial vaccines for plague

Details Orally-administered live bacterial vaccines for plague Orally-administered live bacterial vaccines for plague

A - Human Necessities

61

K

A61K 39/116 (2006.01) A61K 39/00 (2006.01) A61K 39/112 (2006.01) A61P 31/04 (2006.01) C07K 14/24 (2006.01) C12N 1/21 (2006.01) C12N 1/36 (2006.01) C12N 15/31 (2006.01)

Patent

CA 2547425

The invention provides live, attenuated Salmonella bacterial strains that express one or more plague antigens of Yersinia pestis for use in live vaccine compositions that can be orally administered to an individual to protect against plague.

L'invention concerne des souches de bactérie Salmonella vivante atténuée qui expriment un ou plusieurs antigènes de la peste Yersinia pestis, et qui sont destinées à être utilisées dans des compositions de vaccin à souche de bactérie vivante pouvant être administrées par voie orale à un individu pour le protéger contre la peste.

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