Orally administrable compositions comprising cation...

A - Human Necessities – 61 – K

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A61K 47/36 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2368094

Orally administrable compositions comprising cation cross-linked polysaccharides are provided. The compositions have the ability to mask the taste and delay the release of an active material included therein. A novel method for the preparation of the compositions is also provided. The cation cross-linked polysaccharide is preferably selected from alginic acid and demethylated pectin and the composition further comprises a digestible polymer, preferably chosen from starch, starch derivatives, .alpha.-glucans, peptides and polypeptides.

L'invention concerne des compositions contenant des polyosides à cations réticulés pouvant être administrées par voie orale. Ces compositions ont la propriété de masquer le goût et de retarder la libération d'une matière active qu'elles contiennent. L'invention concerne également une nouvelle méthode de préparation de ces compositions. Le polyoside à cations réticulés est choisi de préférence dans le groupe comprenant de l'acide alginique et de la pectine déméthylée. La composition comprend également un polymère digestible, choisi de préférence dans le groupe comprenant de l'amidon, des dérivés de l'amidon, des alpha -glucanes, des peptides et des polypeptides.

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