Orally applicable formulation of quinolone or naphthyridone...

A - Human Necessities – 61 – K

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A61K 31/496 (2006.01) A61K 9/16 (2006.01) A61K 31/4995 (2006.01) A61P 31/04 (2006.01) A61K 31/194 (2006.01)

Patent

CA 2263584

Orally applicable formulations of quinolone or naphthyridone carboxylic acids are prepared by mixing quinolone or naphthyridone carboxylic acids as such or in the form of their water-soluble salts or derivatives, preferably in the form of their aqueous salt solutions, with embonic acid as such or in the form of its water-soluble salts or derivatives, preferably in the form of its aqueous salt solution, in the presence of an excipient, optionally in the presence of auxiliary substances, in the case of dry mixtures in the presence of water, and if required by giving to the thus obtained mixture other forms ready for use.

La présente invention concerne des formulations d'acides dicarboxyliques de quinolone ou de naphtyridone pouvant être administrées par voie orale, préparées par mélange d'acides dicarboxyliques de quinolone ou de naphtyridone en tant que tels ou sous la forme de leurs sels ou dérivés hydrosolubles, de préférence sous la forme de leurs solutions de sels aqueuses, avec de l'acide embonique en tant que tel ou sous la forme de ses sels ou dérivés hydrosolubles, de préférence sous la forme de sa solution de sels aqueuse, en présence d'un excipient, le cas échéant en présence d'auxiliaires, dans le cas de mélanges secs en présence d'eau. Le mélange obtenu est éventuellement converti sous d'autres formes prêtes à l'emploi.

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