Orally bioavailable caffeic acid related anticancer drugs

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 235/34 (2006.01) A61K 31/277 (2006.01) A61K 31/4164 (2006.01) A61K 31/44 (2006.01) A61K 31/4402 (2006.01) A61P 35/00 (2006.01) C07C 255/41 (2006.01) C07D 213/61 (2006.01) C07D 213/64 (2006.01) C07D 233/54 (2006.01)

Patent

CA 2648003

The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. Compounds of the present invention display significant potency as inhibitors of Jak2/STAT3 pathways and downstream targets and inhibit the growth and survival of cancerous cell lines.

La présente invention concerne des composés et leur utilisation pour traiter des maladies de prolifération cellulaire telles que le cancer. Les composés de la présente invention affichent une activité importante comme inhibiteurs des voies Jak2/STAT3 et des cibles en aval et inhibent la croissance et la survie des lignées de cellules cancéreuses.

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