Orally disintegrable tablet forming a viscous slurry

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/20 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/28 (2006.01) A61K 9/46 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) A61K 31/137 (2006.01) A61K 31/426 (2006.01)

Patent

CA 2339992

A dosage form which rapidly disintegrates in the mouth and forms a viscous slurry of either microcapsules or a powder is described. The rapidly disintegrating dosage form is meant for direct oral administration by placing a tablet or capsule in the mouth of a patient. Upon disintegration, a viscosity of the resulting slurry increases so as to form an organoleptically pleasant viscous material which retards the spread of insoluble materials including the drug.

On décrit une forme posologique qui se désagrège rapidement dans la bouche et forme une pulpe visqueuse de microcapsules ou de poudre. Cette forme posologique s'administre directement par voie orale par placement d'un comprimé ou d'une capsule dans la bouche d'un patient. Après désagrégation, la viscosité de la pulpe résultante augmente pour former une matière visqueuse organoleptique agréable qui retarde l'étalement des matières insolubles renfermant le médicament.

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