Orally disintegrating tablet compositions of lamotrigine

A - Human Necessities – 61 – K

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A61K 31/53 (2006.01) A61K 9/00 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2693072

The compositions of the present invention composition comprise a therapeutically effective amount of particles comprising lamotrigine, in combination with granules comprising a disintegrant, and a sugar alcohol and/or a saccharide. These compositions are useful in treating epilepsy and bipolar disorder, particularly for patients with dysphagia, and to improve compliance with bipolar patients.

La présente invention concerne des compositions qui comprennent une quantité thérapeutiquement efficace de particules comprenant de la lamotrigine, en combinaison avec des granules comprenant un délitant, et un alcool de sucre et/ou un saccharide. Ces compositions sont utiles dans le traitement de l'épilepsie et de la psychose maniacodépressive, en particulier chez les patients ayant une dysphagie et pour améliorer l'acceptation des patients bipolaires.

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