Orally disintegrating tablets

Details Orally disintegrating tablets Orally disintegrating tablets

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 47/02 (2006.01) A61K 47/26 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2650498

The present invention describes a directly compressible composite prepared by co-processing a water-soluble excipient and calcium silicate. The present invention further describes the incorporation of the co-processed composite into a tablet formulation. The orally disintegrating tablets are of optimal mechanical strength and disintegrate within 60 seconds in the oral cavity.

La présente invention concerne un composite directement compressible qui est préparé par co-traitement d'un excipient soluble dans l'eau et d'un silicate de calcium. Cette invention porte également sur l'incorporation du composite co-traité dans une formulation de comprimé. Les comprimés se désagrégeant dans la cavité orale présentent une résistance mécanique optimale et se désagrègent en 60 secondes dans la cavité orale.

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