A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/16 (2006.01)
Patent
CA 2658512
The present invention provides an orally dissolvable/ disintegrable, lyophilized, dosage form adapted for direct oral dosing, including an active pharmaceutical ingredient ("API") containing particle which is coated with a lyophilizing solvent protective coating, which protects the form and/or attributes of the particle and/or API, and a matrix. There is also provided a method of making an orally dissolvable/disintegrable lyophilized dosage form in accordance with the present invention, and a method of treating a patient with a dosage form in accordance with the present invention.
L'invention concerne une forme posologique lyophilisée à dissolution/désintégration orale adaptée à un dosage oral direct, cette forme posologique comprenant un ingrédient pharmaceutique actif (IPA) contenant une particule enrobée d'un revêtement protecteur à base d'un solvant lyophilisant qui protège la forme et/ou les attributs de la particule et/ou de l'IPA, ainsi qu'une matrice. L'invention concerne également un procédé de fabrication d'une forme posologique lyophilisée à dissolution/désintégration orale selon l'invention, ainsi qu'une méthode de traitement d'un patient au moyen d'une forme posologique selon l'invention.
Agarwal Vikas
Hamed Ehab
Hillman Lisa
Khankari Rajendra K.
Moe Derek
Cephalon France
Cima Labs Inc.
Smart & Biggar
LandOfFree
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