A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/23 (2006.01) A61K 47/18 (2006.01)
Patent
CA 2529604
Solid pharmaceutical compositions and methods of their use suitable for the oral delivery of pharmacologically active agents, e.g. peptides, comprising a therapeutically-effective amount of a pharmacologically active agent; a crospovidone or povidone; and a delivery agent for said pharmacologically active agent are disclosed. The compositions utilize micronized forms of the delivery agent which provides enhanced bioavailability of pharmacologically active agents, particularly calcitonin.
La présente invention concerne des compositions pharmaceutiques solides et des techniques d'utilisation de celle-ci en vue d'un apport par voie orale d'agents pharmacologiquement actifs, par exemple des peptides, qui comprennent une quantité thérapeutiquement efficace d'agents pharmacologiquement actifs, une crospovidone ou une povidone et un agent d'apport de cet agent pharmacologiquement actif. Ces compositions utilisent des formes micronisée de cet agent d'apport qui permettent d'obtenir une biodisponibilité des agents pharmacologiquement actifs, en particulier la calcitonine. .
Azria Moise
Bateman Simon David
Ghosh Anasuya Ashok
Li Shoufeng
Royce Alan Edward
Fetherstonhaugh & Co.
Novartis Ag
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