Organ arrest, protection and preservation

Details Organ arrest, protection and preservation Organ arrest, protection and preservation

A - Human Necessities

01

N

A01N 1/02 (2006.01)

Patent

CA 2364687

The present invention relates to a method for arresting, protecting and/or preserving an organ which includes administering effective amounts of (i) a potassium channel opener or agonist and/or an adenosine receptor agonist and (ii) local anaesthetic to a subject in need thereof. The present invention also relates to a method for arresting, protecting and/or preserving an organ which comprises adding a composition which includes effective amounts of (i) a potassium channel opener or agonist and/or an adenosine receptor agonist and (ii) a local anaesthetic to the organ. The present invention further provides a pharmaceutical or veterinary composition which includes effective amounts of (i) a potassium channel opener or agonist and/or an adenosine receptor agonist and (ii) a local anaesthetic.

L'invention concerne un procédé d'arrêt, de protection et/ou de préservation d'un organe consistant à administrer des quantités efficaces (I) d'un agent d'ouverture du canal potassique ou un agoniste et/ou un agoniste récepteur de l'adénosine et (ii) d'une anesthésie locale à un sujet malade. L'invention concerne aussi un procédé d'arrêt, de protection et/ou de préservation d'un organe consistant à ajouter une composition renfermant des quantités efficaces (I) d'un agent d'ouverture du canal potassique ou un agoniste et/ou un agoniste récepteur de l'adénosine et (ii) d'une anesthésie locale à un organe. L'invention concerne en outre une composition pharmaceutique ou vétérinaire renfermant des quantités efficaces (I) d'un agent d'ouverture du canal potassique ou un agoniste et/ou un agoniste récepteur de l'adénosine et (ii) d'une anesthésie locale.

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