Organic articles

C - Chemistry – Metallurgy – 08 – F

Patent

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Details

C08F 283/00 (2006.01) A61L 27/18 (2006.01) C07C 323/41 (2006.01) C07C 323/44 (2006.01) C07C 323/51 (2006.01) C07D 295/185 (2006.01) C07H 13/04 (2006.01) C07K 4/00 (2006.01) C07K 14/00 (2006.01) C08F 2/38 (2006.01) C08F 292/00 (2006.01) C08J 7/16 (2006.01) C08J 7/18 (2006.01) G02B 1/04 (2006.01)

Patent

CA 2327743

The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic macromonomers of formula (1) as outlined in the claims to the bulk material surface provided with the initiator radicals and polymerizing said macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.

L'invention concerne de nouveaux matériaux composites comprenant (a) un matériau de base inorganique ou organique dont la surface présente une liaison covalente avec des fractions d'initiateur servant à déclencher une polymérisation radicalaire ; (b) un revêtement de surface hydrophile pouvant être obtenu par mise en application d'un ou de plusieurs macromonomères hydrophiles différents éthylèniquement insaturés représentés par la formule (1) comme le définissent les revendications concernant la surface de matériau de base présentant une liaison covalente avec les radicaux d'initiateur, et par polymérisation desdits macromonomères. Ces matériaux composites possèdent des caractéristiques avantageuses quant à l'adhérence au substrat, la durée de vie, la nature hydrophile, la mouillabilité, la biocompatibilité et la perméabilité et sont, de ce fait, utiles pour fabriquer des articles biomédicaux, tels que des dispositifs ophtalmiques.

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