Organic compounds

Details Organic compounds Organic compounds

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 15/10 (2006.01) A61P 25/00 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2740398

The present invention relates to optionally substituted 3-amino-4,5-dihydro- (1H or 2H)-pyrazolo[3,4- d]pyrimidin- 6(7H)-ones and their 4-imino or 4-thioxo derivatives, e.g., 3- amino-4-(thioxo or imino)-4,5-dihydro-2H- pyrazolo[3,4-d]pyrimidin-6(7H)- ones, 3-amino-4-(thioxo or imino)-4,5-dihydro- 2H-pyrazolo[3,4-d]pyrimidin-6(7H)- ones, 3- amino-4-(thioxo or imino)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6(7H)- ones, processes for their production, their use as pharmaceuticals and pharmaceutical compositions comprising them.

La présente invention concerne des 3-amino-4,5-dihydro-(1H ou 2H)-pyrazolo[3,4-d]pyrimidin-6(7H)-ones ainsi que leurs dérivés 4-imino ou 4-thioxo, par exemple les 3-amino-4-(thioxo ou imino)-4,5-dihydro-2H-pyrazolo[3,4-d]pyrimidin-6(7H)-ones, les 3-amino-4-(thioxo ou imino)-4,5-dihydro-2H-pyrazolo[3,4-d]pyrimidin-6(7H)-ones, les 3-amino-4-(thioxo ou imino)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6(7H)-ones, leurs procédés de production, leur emploi en tant que produits pharmaceutiques et les compositions pharmaceutiques les incluant.

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