Organic compounds

Details Organic compounds Organic compounds

C - Chemistry, Metallurgy

07

D

C07D 491/113 (2006.01) A61K 31/435 (2006.01) A61P 9/00 (2006.01) A61P 13/00 (2006.01) C07D 491/107 (2006.01)

Patent

CA 2708570

The application relates to trisubstituted piperidines of the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R1, R2, X, U, W, m and n have the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.

L'invention porte sur des pipéridines trisubstituées représentées par la formule générale (I) et sur leurs sels, de préférence leurs sels pharmaceutiquement acceptables. Dans cette formule, R1, R2', X, U, W, m et n ont les significations expliquées dans la description. L'invention porte également sur un procédé permettant de préparer ces composés et sur l'utilisation de ces derniers en tant que médicaments, notamment en tant qu'inhibiteurs de la rénine.

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