C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 269/06 (2006.01) C07C 211/28 (2006.01) C07C 271/22 (2006.01) C07D 309/38 (2006.01)
Patent
CA 2626705
The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula (VI), or a salt thereof, wherein R1, R2, R3 and R' are as defined in the specification, and processes of manufacturing this compound including intermediates.
L~invention concerne un nouveau procédé, de nouvelles étapes de procédé et de nouveaux intermédiaires utiles pour la synthèse de composés pharmaceutiquement actifs, notamment d~inhibiteurs de la rénine, tels que l~Aliskiren. L~invention concerne entre autres un procédé de fabrication d~un composé de formule (VI), ou d~un sel dudit composé, dans laquelle R1, R2, R3 et R' sont tels que définis dans la description, ainsi que des procédés de fabrication de ce composé, y compris des intermédiaires.
Bonnet Ludovic
Gorsuch Stephen
Ichihara Osamu
Mears Richard
Mykytiuk John
Fetherstonhaugh & Co.
Novartis Ag
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