Organic compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/04 (2006.01)

Patent

CA 2640488

The present invention relates to novel aza-thia-benzoazulene derivatives of formula I as defined in the claims, their preparation, the use of these novel compounds for the preparation of pharmaceutical compositions, the use of these novel compounds and compositions for managing arthritis and arthritis-related conditions as well as in the treatment of pain in animals and humans. More particularly, the present invention relates to pharmaceutical, preferably veterinary compositions and methods for reducing inflammation and pain associated with acute inflammation of body parts, particularly joints, due to injury or due to arthritic conditions or other disease conditions.

La présente invention concerne de nouveaux dérivés d'aza-thia-benzoazulène de formule I comme défini dans les revendications, leur synthèse, l'utilisation de ces nouveaux composés dans l'élaboration de compositions pharmaceutiques, l'utilisation de ces nouveaux composés et compositions dans la gestion de l'arthrite et des états pathologiques liés à l'arthrite ainsi que dans le traitement de la douleur chez les animaux et les êtres humains. La présente invention concerne plus particulièrement des compositions pharmaceutiques, préférentiellement vétérinaires, et des méthodes de réduction de l'inflammation et de la douleur associées à une inflammation aiguë des parties du corps, en particulier les articulations, du fait d'une blessure, d'états arthritiques ou d'autres états pathologiques.

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