Organic compounds and their uses

Details Organic compounds and their uses Organic compounds and their uses

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/4375 (2006.01) A61K 31/444 (2006.01) A61K 31/501 (2006.01) A61K 31/506 (2006.01) A61K 31/53 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2672518

The present application describes organic compounds of formula (I), wherein m is 0 or 1; n is 0 or 1; A1, A2, A3 and A4 are each, independently, C, C(H) or N; that are useful for the treatment and therapies for protein kinase-associated disorders. They are in particular useful in the treatment or prevention on amelioration of one or more symptoms of cancer, inflammation, cardiac hypertrophy, and HIV by modulating the activity of protein kinases, such as CDK1, CDK2, CDK3, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, and combinations thereof.

L'invention concerne des composés organiques utiles pour le traitement, la prévention et/ou l'amélioration de pathologies.

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