C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 38/04 (2006.01)
Patent
CA 2460300
The invention relates to biologically active molecules, interacting with thrombin and inhibiting the same. The invention particularly relates to molecules of general formula (I): Y1-(NH-X1-C=O)-(NH-X2-C=O)-(NH-X3-C=O)-(NH- X4-C=O)-(NH-X5-C=O)(NH-X6-C=O)-Y2, in which Y1, Y2 and X1-6 have the meanings given in the description, N.-or C-terminal shortened variants of said compounds and the use thereof for the production of medicaments.
L'invention concerne des molécules à activité biologique qui entrent en interaction avec la thrombine et l'inhibent. L'invention concerne notamment des molécules de formule générale Y?1¿-(NH-X?1¿-C=O)-(NH-X?2¿-C=O)-(NH-X?3¿-C=O)-(NH-X?4¿-C=O)-(NH-X?5¿-CO)(NH-X?6¿-C=O)-Y?2¿, dans laquelle Y?1¿, Y?2¿ et X?1-6¿ ont les significations mentionnées dans la description, ainsi que des variantes tronquées en terminal N ou C de ces composés et leur utilisation pour produire des médicaments.
Novel Science International Gmbh
Robic
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