B - Operations – Transporting – 01 – J
Patent
B - Operations, Transporting
01
J
B01J 20/32 (2006.01) B01J 20/286 (2006.01) B01J 20/29 (2006.01) C07B 57/00 (2006.01)
Patent
CA 2664855
The present invention provides an organic-inorganic hybrid chiral sorbent for chiral resolution of various racemic compounds viz. racemic mandelic acid, 2- phenyl propionic acid, diethyl tartrate, 2,2'-dihydroxy-1,1 '-binaphthalene (BINOL) and cyano chromene oxide with excellent chiral separation (enantiomeric excess, 99 %) in case of mandelic acid under medium pressure column chromatography. These optically pure enantiomers find applications as intermediates in pharmaceutical industries.
La présente invention concerne un sorbant chiral hybride organique - inorganique pour une résolution chirale de différents composés racémiques tels que l'acide mandélique racémique, l'acide propionique 2-phényl, le tartrate de diéthyle, 2,2'-dihydroxy-1,1 '-binaphthalène (BINOL) et l'oxyde de chromène cyanique avec une excellente séparation chirale (excès énantiomère, 99 %) dans le cas d'acide mandélique sous chromatographie sur colonne à pression moyenne. Ces énantiomères optiquement purs trouvent des applications en tant qu'intermédiaires dans les industries pharmaceutiques.
Abdi Syed Hasan Razi
Agarwal Santosh
Jasra Raksh Vir
Khan Noor-Ul Hasan
Kureshy Rukhsana Ilyas
Council Of Scientific & Industrial Research
Stikeman Elliott Llp
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