Organic/inorganic hybrid nanoparticulates made from iron...

C - Chemistry – Metallurgy – 07 – F

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C07F 15/02 (2006.01) A61K 8/30 (2006.01) A61K 9/14 (2006.01) A61K 47/08 (2006.01) A61K 49/18 (2006.01) A61P 17/00 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2699480

The invention relates to nanoparticles made from organometallic hybrid materials made from iron carboxylates, used for example as contrast agents. The particles can also be used for the encapsulation and vectoring of molecules of interest such as active3 pharmaceutical agents, cosmetically interesting compounds and markers. Apart from the intrinsic properties thereof for imaging, said nanoparticles give good results in terms of capacity for loading with medicaments and in biocompatibility.

La presentee invention se rapporte a des nanoparticules de materiau hybride metal-organique a base de carboxylates de fer, utilisables par exemple comme agent de contraste. Ces particules peuvent egalement etre utilisees pour l'eiranagasinement et la vectorisation de molecules d'interet telles que des principes pharmaceutiquement actifs, des composes d'interet en cosmetique et des marqueurs. Outre leurs proprietes intrinseques en imagerie, ces nanoparticules presentent de bons resultats en terme de capacites de charge en actifs medicamenteux et de biocompatibilite.

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