Organic nitrate sublingual tablets

Details Organic nitrate sublingual tablets Organic nitrate sublingual tablets

A - Human Necessities

61

K

167/166, 167/251

A61K 9/36 (2006.01) A61J 3/10 (2006.01) A61K 31/21 (2006.01) C08F 126/10 (2006.01)

Patent

CA 1058076

ABSTRACT OF THE DISCLOSURE This invention relates to a novel organic nitrate tablet com- position, comprising polyvinylpyrrolidone and an organic nitrate thera- peutic agent, and to compressed tablets thereof, and more particularly to a new and improved form of compressed tablet for sublingual administration to the prophylaxis and treatment of acute coronary attacks, which is capable of rapid disintegration when administered thereby allowing rapid buccal ab- sorption of the therapeutic agent contained in said tablet. The present invention also relates to a method of producing sublingual tablets, contain- ing polyvinylpyrrolidone and an organic nitrate therapeutic agent, with an improved formulation which gives an extended shelf life and stabilized potency to the tablets.

224995

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