Organic platinum complexes and uses

Details Organic platinum complexes and uses Organic platinum complexes and uses

C - Chemistry, Metallurgy

07

F

260/429.4

C07F 15/00 (2006.01) C07C 59/245 (2006.01)

Patent

CA 1171425

ABSTRACT OF THE DISCLOSURE An organic complex of platinum, cis-isocitrato (1,2-diaminocyclohexane) platinum (II) having improved anti-tumor activity and water-solubility. The complex is prepared by reacting cis-dichloro (1,2-diaminocyclo- hexane) platinum (II) with silver nitrate, removing the silver chloride formed, and reacting the resulting liquid with trisodium isocitrate. The complex is admin- istered in the form of a pharmaceutical composition.

376517

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