Organic salts and method for producing chiral organic compounds

C - Chemistry – Metallurgy – 07 – B

Patent

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C07B 53/00 (2006.01) C07C 29/88 (2006.01) C07C 45/62 (2006.01) C07C 47/02 (2006.01) C07C 47/21 (2006.01) C07C 47/228 (2006.01) C07C 47/23 (2006.01) C07C 47/24 (2006.01) C07C 49/395 (2006.01) C07C 49/403 (2006.01) C07C 49/413 (2006.01) C07C 49/657 (2006.01) C07C 67/08 (2006.01) C07C 69/007 (2006.01) C07D 301/14 (2006.01)

Patent

CA 2642784

The invention relates to a method for producing chiral organic compounds by asymmetric catalysis, using ionic catalysts comprising a chiral catalyst anion. The claimed method is suitable for reactions which are carried out over cationic intermediate stages, such as imnium ions or acyl pyridinium ions. The invention enables the production of chiral compounds with high ee values, that until now could only be obtained by means of costly purification methods.

L'invention concerne un procédé de production de composés organiques chiraux par catalyse, procédé selon lequel des catalyseurs ioniques présentant un anion de catalyseur chiral sont utilisés. Ledit procédé convient à la mise en oeuvre de réactions se produisant sur des états intermédiaires cationiques, tels que sur des ions imnium ou sur des ions acylpyridinium. Ce procédé permet de produire des composés chiraux à excès énantiomère élevé qui n'étaient jusqu'à présent obtenus que par des procédés de purification coûteux.

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