C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 7/02 (2006.01) A61K 8/58 (2006.01) A61K 8/97 (2006.01) A61Q 3/00 (2006.01) A61Q 5/00 (2006.01) A61Q 19/00 (2006.01) C07F 7/04 (2006.01)
Patent
CA 2604751
This invention describes materials containing organic silica, used in cosmetic for external uses (gel, cream or lotion) or for internal uses (microbeads/beads, tablets or solutions). These materials are vegetable extracts such as bamboo or algae which constitute richest sources in organic silica (more soluble and assimilable). After extraction in a basic medium, the organic silica extract can form a stable complex at acidic pH in presence of stabilizers such as gelatin, collagen, polyethylene glycol and/or chitosan, etc. These complexes can be used for cosmetic applications in gel, lotion and cream or as a matrix in order to immobilize various bioactive molecules. For internal uses, the soluble form of monomeric or oligomeic silicic acid is necessary to preserve its assimilability. In this context, the addition of stabilizers (gelatin and/or collagen) or the functionalization of silicic acid is possible to improve its solubility and biodisponibility.
Cette invention décrit des matières contenant de la silice organique, utilisées en cosmétique pour des usages externes (gel, crème ou lotion) ou pour des usages internes (microbilles/billes, comprimés ou solutions). Ces matières sont des extraits de plantes telles que du bambou ou des algues qui constituent les sources les plus riches en silice organique (plus soluble et assimilable). Après extraction dans un milieu basique, l'extrait contenant de la silice organique peut former un complexe stable à un pH acide en présence de stabilisants tels que la gélatine, le collagène, le polyéthylèneglycol et/ou le chitosane, etc. Ces complexes peuvent être utilisés pour des applications cosmétiques en gel, lotion et crème ou en tant que matrice afin d'immobiliser différentes molécules bioactives. Pour des usages internes, la forme soluble de l'acide silicique monomérique ou oligomérique est nécessaire pour conserver son caractère assimilable. Dans ce contexte, l'ajout de stabilisants (gélatine et/ou collagène) ou la fonctionnalisation de l'acide silicique est possible pour améliorer sa solubilité et sa biodisponibilité.
Laboratoires Mauves Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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