Organo cuprate process for cefprozil

C - Chemistry – Metallurgy – 07 – D

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C07D 501/04 (2006.01) C07D 501/00 (2006.01)

Patent

CA 2037688

ABSTRACT OF THE DISCLOSURE Cephalosporin intermediates having a replacable organosulfonlyoxy or heterocyclothio group in the 3-position undergo a carbon alkylation process with organocopper reagents to provide 3-hydrocarbon substituted cephalosporin antibiotics.

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