C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
167/119, 260/434
C07F 7/30 (2006.01) A61K 31/28 (2006.01)
Patent
CA 1322761
72057-10 ABSTRACT OF THE DISCLOSURE Disclosed are organogermanium compound of the formulae Image and Image (1,2) (3,4-O,S) (wherein X is halogen, R is hydrogen, lower alkyl or phenyl, R1 is -NHCOCH3 or -NH2.HY, R2 is -NHCOCH3 or -NH2 and Z is O or S). The compounds (3,4-O,S), particularly when R2 is -NH2, has an ability to suppress the formation of Amadori rearrangement product and are useful as a therapeutic agent.
609553
Kakimoto Norihiro
Nakamura Kunie
Yoshihara Toru
Asai Germanium Research Institute Co. Ltd.
Smart & Biggar
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