Orodispersible domperidone tablets

Details Orodispersible domperidone tablets Orodispersible domperidone tablets

A - Human Necessities

61

K

A61K 31/454 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2645629

The present invention relates to an orodispersible tablet comprised of, by weight: a maximum of 15% of a low-dose, therapeutically active substance; from 55% to 70% of mannitol of a particle size between 30 µm and 300 µm; at least 2% of maltodextrin; from 3.5% to 8% of croscarmellose sodium; from 10% to 20% of microcrystalline cellulose; from 0.5% to 1.5% of magnesium stearate; and from 1% to 5% of flavoring (s) and sweetener (s).

La présente invention concerne un comprimé orodispersible comprenant, en poids : au maximum 15% d'une substance thérapeutiquement active à faible dose ; de 55% à 70% de mannitol ayant une taille de particule comprise entre 30 µm et 300 µm ; au moins 2% de maltodextrine ; de 3,5% à 8% de croscarmellose sodique ; de 10% à 20% de cellulose microcristalline ; de 0,5% à 1,5% de stéarate de magnésium ; et de 1% à 5% d'un ou plusieurs arômes et édulcorants.

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