Orodispersible mannitol

Details Orodispersible mannitol Orodispersible mannitol

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2727109

The subject of the invention is coagglomerates of mannitol, the laser volume-average diameter D4,3 of which is between 1 and 200 µm, and of granular starch, characterized in that they have a disintegration behaviour determined according to a test A such that the relaxation time measured is between 30 and 100 seconds and the swelling force is between 0.8 and 3.0 N.

L'invention a pour objet des Coagglomérats de mannitol, dont le diamètre moyen volumique laser D4,3 est compris entre 1 et 200 µm, et d'amidon granulaire caractérisés en ce qu'ils présentent un comportement au délitement déterminé selon un test A tel que le temps de relaxation mesuré soit compris entre 30 et 100 secondes et la force de gonflement soit comprise entre 0,8 et 3,0 N.

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