Oromucosal formulation and process for preparing the same

Details Oromucosal formulation and process for preparing the same Oromucosal formulation and process for preparing the same

A - Human Necessities

61

K

A61K 31/4164 (2006.01) A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2505139

An oromucosal formulation comprising as an active ingredient a substituted imidazole derivative of formula (I) [please enter chemical formula here] where Y is -CH2- or -CO-, R1 is halogen or hydroxy, R2 is H or halogen and R3 is H or lower alkyl, or an acid addition salt thereof, together with additives conventionally used in oromucosal formulations, and a process for its preparation.

L'invention concerne une formulation administrée à la muqueuse orale contenant, en tant que principe actif, un dérivé imidazole substitué de la formule (I) dans laquelle Y représente -CH¿2?- ou -CO-, R¿1? représente halogène ou hydroxy, R¿2? représente H ou halogène et R¿3? représente H ou alkyle inférieur, ou un sel d'addition d'acide de celui-ci, avec les additifs utilisés classiquement dans les formulations pour muqueuse orale et un procédé permettant sa préparation.

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