A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/185 (2006.01) A61K 31/205 (2006.01) A61K 31/505 (2006.01) A61K 31/66 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2698135
The present invention relates to the use of osmolytes for treating allergic or viral respiratory diseases, e.g. allergic rhinitis (hay fever) as well as rhinovirus and/or adenovirus infections. The invention also relates to a medicament preparation containing one or more compounds from the group of osmolytes. The group of osmolytes used in the invention comprises various low-molecular substances , more specifically ectoine, 4,5,6,7-tetrahydro-2-methyl-1H-[1,3]-diazepine-4-S-carboxylic acid (homoectoine), hydroxyectoine, di-myo-inositol-phosphate (DIP), cyclic 2,3-diphosphoglycerate (cDPG), 1,1-diglycerol phosphate (DGP), .beta.--mannosylglycerate (firoin), .beta.-mannosylglyceramide (firoin-A), dimannosyl--diinositol phosphate (DMIP), glucosylglycerol, taurine, betaine, citrulline, and/or a derivative, e.g. an acid, salt, or ester of said compounds.
La présente invention concerne l'utilisation d'osmolytes pour traiter des affections des voies respiratoires d'origine allergique ou virale, telles la rhinite allergique (rhume des foins) et les infections à rhinovirus et/ou adénovirus. L'invention concerne également une préparation pharmaceutique contenant un ou plusieurs composés du groupe des osmolytes. Le groupe des osmolytes désignés dans l'invention comprend différentes substances de faible poids moléculaire, notamment l'ectoïne, l'acide 4,5,6,7-tétrahydro-2-méthyl-1H-[1,3]-diazépine-4-S-carboxylique (homoectoïne), l'hydroxyectoïne, le di-myo-inositolphosphate (DIP), le 2,3-diphosphoglycérate cyclique (cDPG), le 1,1-di-glycérophosphate (DGP), le ß-mannosylglycérate (firoïne), le ß-mannosylglycéramide (firoïne-A), le di-mannosyl-di-inositolphosphate (DMIP), le glucosylglycérol, la taurine, la bétaïne, la citrulline et/ou un dérivé, p. ex. un acide, un sel ou un ester de ces composés.
Krutmann Jean
Lentzen Georg
Schwarz Thomas
Bitop Ag
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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