Osmotic drug delivery devices with hydrophobic wall materials

Details Osmotic drug delivery devices with hydrophobic wall materials Osmotic drug delivery devices with hydrophobic wall materials

B - Operations, Transporting

01

D

B01D 69/02 (2006.01) A61K 9/00 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2115648

Osmotically driven drug delivery devices with walls of porous hydrophobic materi- al as the sole diffusion-limiting wall component are disclosed. Despite pores which are considerably larger than the molecular dimensions of non-volatile species in the interior of the device, despite pores which by their hydrophobic character do not permit the pas- sage of liquid water, and despite the absence of a cellulosic semipermeable membrane, the devices absorb water by osmosis without loss of the non-volatile species, and function in a manner analogous to osmotic pumps of the prior art. By permitting the use of hydrophob- ic substances as the wall material, the invention permits the device to be constructed en- tirely from biodegradable materials.

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