Osteogenesis promotion with use of vitamin d derivatives

A - Human Necessities – 61 – K

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167/147

A61K 31/59 (2006.01)

Patent

CA 2010982

An osteogenesis promotion with use of a vitamin D derivative of the formula: (see formula I) wherein R1, R2 and R3, which may be the same or different, each represents a hydrogen atom or a hydroxyl group; and R4 is a hydrogen atom or a lower alkyl group having 4 - 6 carbon atoms that may or may not be substituted by a hydroxyl group, are disclosed. A pharmaceutical composition comprising the above derivatives is useful as a therapeutic agent for osteoporosis.

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