Osteogenic composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/18 (2006.01) A61K 31/4015 (2006.01) A61K 31/715 (2006.01) A61K 31/765 (2006.01) A61K 31/785 (2006.01) A61K 31/80 (2006.01) A61P 1/00 (2006.01) A61P 19/00 (2006.01)

Patent

CA 2513712

The present invention relates to pharmaceutical composi-tions containing a synergistic amount of at least one bone morphogenetic protein (BMP) and a synergistic amount of at least one pyrrolidone optionally in a pharmaceutically acceptable carrier, such as a biodegradable polymer. The present invention further relates to methods of treating or-thopaedic and dental, including periodontal, diseases by simultaneously administering a synergistic amount of at least one bone morphogenetic protein (BMP) and a syner-gistic amount of at least one pyrrolidone optionally in a pharmaceutically acceptable carrier to patients in need of such treatment.

La présente invention concerne des compositions pharmaceutiques contenant une quantité synergique d'au moins une protéine morphogénétique osseuse (BMP) et une quantité synergique d'au moins une pyrrolidone éventuellement dans un excipient pharmaceutiquement acceptable, tel qu'un polymère biodégradable. Ladite invention concerne également des méthodes de traitement de maladies orthopédiques et dentaires, y compris parodontales, par l'administration simultanée d'une quantité synergique d'au moins une protéine morphogénétique osseuse (BMP) et d'une quantité synergique d'au moins une pyrrolidone éventuellement dans un excipient pharmaceutiquement acceptable à des patients nécessitant un traitement de ce type.

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