C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/077 (2010.01) C12N 5/0775 (2010.01) A61K 35/32 (2006.01) A61M 31/00 (2006.01) A61P 19/08 (2006.01)
Patent
CA 2710571
The invention relates to methods for osteogenic differentiation of human bone marrow stem cells (BMSC) or mesenchymal stem cells (MSC), in particular using human plasma or serum and FGF and TGFB growth factors. The invention also provides the so-obtained cells and cell populations, as well as further products comprising such and uses thereof in bone therapy.
L'invention porte sur des procédés de différenciation ostéogénique de cellules souches de moelle osseuse humaines (BMSC) ou de cellules souches mésenchymateuses (MSC), en particulier à l'aide de plasma ou sérum humain et de facteurs de croissance FGF et TGFB. L'invention porte également sur les cellules et populations de cellules ainsi obtenues ainsi que sur d'autres produits comprenant celles-ci et sur leurs utilisations en thérapie osseuse.
Badoer Cindy
Bastianelli Enrico
Pesesse Xavier
Bone Therapeutics S.a.
Borden Ladner Gervais Llp
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