Osteonectin based toxic gene therapy for the treatment of...

Details Osteonectin based toxic gene therapy for the treatment of... Osteonectin based toxic gene therapy for the treatment of...

A - Human Necessities

01

N

A01N 43/04 (2006.01) A61K 48/00 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2374141

The present invention relates to promoters, enhancers and other regulatory elements that direct expression within tumor and tissue cells with calcification potential. Specifically provided are expression vectors, host cells, and transgenic animals comprising an OSN regulatory region.

La présente invention concerne des promoteurs, des activateurs et d'autres éléments régulateurs qui régulent l'expression dans des cellules de tumeurs et de tissus possédant un potentiel de calcification. L'invention concerne spécifiquement des vecteurs d'expression, des cellules hôtes et des animaux transgéniques comportant une séquence régulatrice de l'ostéonectine (OSN).

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