A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 39/00 (2006.01) A61K 39/02 (2006.01) A61K 39/40 (2006.01) C07K 1/00 (2006.01) C07K 16/00 (2006.01) C07K 16/12 (2006.01)
Patent
CA 2382221
The present invention relates to three outer membrane proteins conserved among Gram-negative bacteria, OmpA, PAL, and MLP. The invention provides vaccines and polypeptides useful for passive and active immunization against Gram- negative bacteria, as well as methods of preventing and treating Gram-negative sepsis.
la présente invention concerne trois protéines de membrane externe conservées parmi des bactéries Gram négatif, des OmpA, des phénylalanines ammoniac-lyases et des MLP. L'invention porte également sur des vaccins et des polypeptides utiles pour l'immunisation active et passive contre les bactéries Gram négatif, ainsi que sur des procédés destinés à prévenir et à traiter la septicémie Gram négatif.
Judith Hellman
Kurnick James T.
Warren H. Shaw
Smart & Biggar
The General Hospital Corporation
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