Ovary-specific genes and proteins

Details Ovary-specific genes and proteins Ovary-specific genes and proteins

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 15/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C12N 15/10 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2445410

The present invention relates generally to ovary-specific genes (O1-180, O1- 184 and O1-236) and the proteins they encode. Also provided are methods for detecting cell proliferative or degenerative disorders in reproductive tissues. Yet further, the invention provides methods for screeing of compounds that interact and/or modulate the expression or activity of the ovary-specific genes. These compounds are possible contraceptive agents and/or fertility agents.

La présente invention concerne globalement des gènes spécifiques aux ovaires (O1-180, O1-184 et O1-236) et les protéines codées par ces gènes. L'invention concerne également des méthodes destinées à la détection de troubles induisant une prolifération ou une dégénérescence cellulaire dans les tissus reproducteurs. L'invention concerne également des méthodes destinées au criblage de composés qui interagissent avec et/ou qui modulent l'expression ou l'activité des gènes spécifiques aux ovaires. Ces composés sont d'éventuels agents contraceptifs et/ou agents fertilisants.

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