Ovine growth hormone releasing factor

Details Ovine growth hormone releasing factor Ovine growth hormone releasing factor

C - Chemistry, Metallurgy

07

K

167/205, 530/7.1

C07K 14/60 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1247604

GRF ANALOGS ABSTRACT OF THE DISCLOSURE Synthetic peptides are extremely potent in stimulating the release of pituitary GH in mammals because they are the replicates of the native (hormone) releasing factor of the hypothalamus of the particular species, i.e. ovine. These peptides contain the following sequence: Image The peptide or a biologically active fragment thereof, or analogs thereof having well-known substitutions and/or additions, as well as nontoxic salts of any of the foregoing, may be administered to mammals and may be used diagnostically. The peptides are particularly useful in stimulating the release of GH so as to accelerate growth in warm-blooded non-human animals of the particular species and/or to improve aquiculture.

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