Ovulation-preventing agent for hormonal contraception

Details Ovulation-preventing agent for hormonal contraception Ovulation-preventing agent for hormonal contraception

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 31/57 (2006.01)

Patent

CA 2079002

Ovulation-inhibiting means for hormonal contraception, comprising two hormone constituents packed spatially separate in a packing unit intended for chronologically sequential, oral administration, each thereof being composed of a plurality of daily hormone units accommodated spatially separate and individually removable in the packaging unit, whereby a first of said hormone constituents contains essentially only an estrogen preparation effecting a disturbance of the follicle stimulation as hormonal agent but the second hormone constituent contains an estrogen preparation and a gestagen preparation at least in a dose adequate for inhibiting ovulation, characterized in that the total number of daily hormone units is equal to the total number of days in the desired cycle; in that the first hormone constituent covers 5 through 14 daily units and the second hormone constituent covers 23 through 14 daily units; and in that the number of daily units of the first hormone constituent is lower than the number of daily units of the second hormone constituent.

Produit servant à inhiber l'ovulation pour contraception hormonale, comprenant deux composants hormonaux emballés séparément dans une unité d'emballage visant une administration orale, séquentielle et chronologique. Chaque composant comprend plusieurs unités hormonales quotidiennes séparées et enlevables individuellement de l'unité d'emballage. Un premier composant hormonal contient essentiellement seulement une préparation d'oestrogène qui entraîne une perturbation de la stimulation folliculaire comme agent hormonal. Le second composant hormonal, pour sa part, contient une préparation d'oestrogène ainsi qu'une préparation de gestagène, au moins en une dose adéquate pour inhiber l'ovulation. Il se caractérise par le fait que : le nombre total d'unités hormonales quotidiennes équivaut au nombre total de jours dans le cycle désiré; le premier composant hormonal couvre de 5 à 14 unités quotidiennes et le second composant hormonal couvre de 23 à 14 unités quotidiennes; le nombre d'unités quotidiennes du premier composant hormonal est inférieur au nombre d'unités quotidiennes du second composant hormonal.

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