C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 31/00 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C07K 16/28 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2489004
The present invention provides binding molecules, such as human binding molecules, that bind to and stimulate the human 0X40-receptor. The invention also provides nucleic acids encoding such binding molecules. Methods for producing such binding molecules are also provided by the present invention. Said binding molecules and nucleic acids are useful in the stimulation of human T-cells, and can be used to enhance antigen-specific immune responses.
Cette invention concerne des molécules de liaison, telles que des molécules de liaison humaines, qui se lient au récepteur OX40 humain et qui le stimulent. Cette invention concerne également des acides nucléiques codant ces molécules de liaison, ainsi que des procédés de production de ces molécules de liaison. Ces molécules de liaison et ces acides nucléiques servent à stimuler les lymphocytes T humains et peuvent être utilisés pour renforcer les réponses immunitaires spécifiques aux antigènes.
Bakker Adrianus Quirinus
Bakker Alexander Berthold Hendrik
Meester-Rood Pauline Marie Louise
Borden Ladner Gervais Llp
Crucell Holland B.v.
LandOfFree
Ox40 (=cd134) receptor agonistic and therapeutic use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ox40 (=cd134) receptor agonistic and therapeutic use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ox40 (=cd134) receptor agonistic and therapeutic use will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1737917